A research team led by the Technical University of Munich (TUM) has successfully used specific enzymes to destroy the genetic information of SARS-CoV-2 directly after the virus penetrates the cell. The findings could serve ...
Cell & Microbiology
Mar 2, 2022
0
42
The amount of structural data on protein drug targets continues to grow. However, successfully mining this data to form testable hypotheses that drive drug discovery can prove challenging. Selectivity for the target protein ...
Biochemistry
Mar 2, 2022
0
11
WEHI researchers have produced the first molecular images of an enzyme that controls proteins to signal and communicate with each other in human cells. The discovery could help to solve the mystery cause of a rare group of ...
Cell & Microbiology
Jan 10, 2022
0
96
The virus that causes COVID-19 has adopted some stealth moves to stay alive and kicking, and one secret to its success is hiding from the immune system by spreading through cell-to-cell transmission, a new study has found.
Cell & Microbiology
Dec 23, 2021
0
200
Researchers at MIT and Harvard University have designed a way to selectively turn on gene therapies in target cells, including human cells. Their technology can detect specific messenger RNA sequences in cells, and that detection ...
Biotechnology
Oct 28, 2021
0
388
Supercomputer simulations by RIKEN researchers have revealed how drug binding to a protein target changes as the surrounding environment becomes more cluttered with other proteins. These simulations could help improve drug ...
Biotechnology
Oct 21, 2021
0
73
Proteins are the molecular machines of all living cells and have been exploited for use in many applications, including therapeutics and industrial catalysts. To overcome the limitations of naturally occurring proteins, protein ...
Biotechnology
Oct 8, 2021
0
176
Researchers use synthesized small molecule tools, known as chemical probes, with druglike properties to identify specific types of proteins in order to find potential new drug leads. However, currently-available technologies ...
Biochemistry
Sep 9, 2021
0
82
When agricultural weeds evolve resistance to herbicides, they do it in one of two ways. In target-site resistance, a tiny mutation in the plant's genetic code means the chemical no longer fits in the protein it's designed ...
Plants & Animals
Aug 16, 2021
0
11
A team of researchers from the University of California, San Francisco (UCSF), Stanford University, and the California Academy of Sciences (CAS) has uncovered new clues as to how poisonous frogs and birds avoid intoxicating ...
Plants & Animals
Aug 5, 2021
0
14
