Programming pH: New technique could accelerate DNA synthesis

pH—the concentration of protons in a watery solution—indicates how acidic the solution is. It regulates a broad range of natural and engineered chemical processes, including the synthesis of designed DNA sequences for ...

Turning white blood cells into medicinal microrobots with light

Medicinal microrobots could help physicians better treat and prevent diseases. But most of these devices are made with synthetic materials that trigger immune responses in vivo. Now, for the first time, researchers reporting ...

Nanoparticle 'backpacks' restore damaged stem cells

Within a newborn's umbilical cord lie potentially life-saving stem cells that can be used to fight diseases like lymphoma and leukemia. That is why many new parents elect to store ("bank") their infant's stem cell-rich umbilical ...

Scientists engineer synthetic DNA to study 'architect' genes

Researchers at New York University have created artificial Hox genes—which plan and direct where cells go to develop tissues or organs—using new synthetic DNA technology and genomic engineering in stem cells.

Another step toward synthetic cells

Building functional synthetic cells from the bottom-up is an ongoing effort of scientists around the globe. Their use in studying cellular mechanisms in a highly controlled and pre-defined setting creates great value for ...

New yeast model can improve protein production

Microorganisms, such as baker's yeast, can be used as cell factories to produce different chemicals and proteins, such as commonly used pharmaceuticals as insulin. By modifying the cell factories researchers are trying to ...

New technology protects authenticity of engineered cell lines

Advances in synthetic biology and genome editing have led to a growing industry to develop customized cell lines for medical research. These engineered cell lines, however, can be vulnerable to misidentification, cross-contamination ...

Structure of key protein for cell division puzzles researchers

Human cell division involves hundreds of proteins at its core. Knowing the 3D structure of these proteins is pivotal to understand how our genetic material is duplicated and passed through generations. The groups of Andrea ...

Thwarting cellular enzyme can fight viral infections

FMI researchers have identified a synthetic protein that dampens the activity of a cellular pathway involved in viral infection. The findings could help to develop drugs that combat viruses such as influenza A and Zika.

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