Researchers assemble library of sugars

Sugar structures called GAGs are present in almost all tissues in the human body, and have important functions in various diseases. The understanding of these sugar structures is limited, because tools to study them have ...

Sleeping sickness parasites camouflage themselves with sugar

It has long been known that the pathogens causing sleeping sickness evade the immune system by exchanging their surface proteins. But now scientists at the German Cancer Research Center (DKFZ) have found an additional parasite ...

Sticking sugar to protein

ETH researchers have succeeded in determining the 3-D structure of the enzyme that attaches sugar chains to proteins – a breakthrough that they recently published in the journal Science.

Glycocluster design could lead to targeted drug delivery

A team led by researchers at the RIKEN Biofunctional Synthetic Chemistry Laboratory in Japan has developed a way to engineer glycan complexes—clusters of sugar chains attached to proteins or lipids—in a way that allows ...

Study identifies new way to suppress lung tumors

Lung cancer cell growth depends on certain proteins that require the addition of sugar molecule chains to become active. Scientists have long thought that the addition of these sugar chains is like an on or off switch, and ...

Decoding 'sweet codes' that determine protein fates

We often experience difficulties in identifying the accurate shape of dynamic and fluctuating objects. This is especially the case in the nanoscale world of biomolecules. The research group lead by Professor Koichi Kato of ...

New insights in survival strategies of bacteria

Bacteria are particularly ingenious when it comes to survival strategies. They often create a biofilm to protect themselves from a hostile environment, for example during treatment with antibiotics. A biofilm is a bacterial ...

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