New sample holder for protein crystallography

Proteins are huge molecules that often have complex three-dimensional structure and morphology that can include side chains, folds, and twists. This three-dimensional shape is often the determining factor of their function ...

Gip1 structure places G proteins in lockdown

Heterotrimeric G proteins are important in G protein-coupled receptor signaling, which plays many roles in the detection of various environmental stimuli, including hormones, neurotransmitters, light, smells, and chemical ...

Researchers describe the role of water in protein folding

A study developed by researchers at the Faculty of Physics of the University of Barcelona (UB), published in the journal Physical Review Letters, describes the contribution of water to the three-dimensional structure of proteins ...

The protein problem

The importance of proteins is difficult to overstate; they play a critical role in countless biological processes. An enhanced understanding of their structure and function is essential to advancing the state of the art in ...

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