Artificial intelligence takes structural biology to the next level

A scientist at Karolinska Institutet reports that machine learning can be used to gain insights into molecular events that change the shape of proteins after they are made, regulating their ability to interact with each other. ...

Heating proteins to understand how genes work

Understanding how genes work and how they interact with one another is a major goal of biology. This poses huge challenges in terms of both methods and the sheer numbers of experiments required. Recent advances have transformed ...

Developing an AI solution to 50-year-old protein challenge

In a major scientific advance, the latest version of DeepMind's AI system AlphaFold has been recognized as a solution to the 50-year-old grand challenge of protein structure prediction, often referred to as the 'protein folding ...

Dual brake on transport protein prevents cells from exploding

A high concentration of salt or sugar in the environment will dehydrate microorganisms and stop them from growing. To counter this, bacteria can increase their internal solute concentration. Scientists from the University ...

Chemists discover the structure of a key coronavirus protein

MIT chemists have determined the molecular structure of a protein found in the SARS-CoV-2 virus. This protein, called the envelope protein E, forms a cation-selective channel and plays a key role in the virus's ability to ...

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