Researchers reveal the first cryo-EM structures of NSD2 and NSD3 in complex with nucleosome
The nuclear receptor–binding SET Domain (NSD) family protein is closely connected with many cancers. However, their molecular mechanism remains unknown.
The nuclear receptor–binding SET Domain (NSD) family protein is closely connected with many cancers. However, their molecular mechanism remains unknown.
Biotechnology
Dec 24, 2020
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193
Notch receptors are core components of the signaling pathways that regulate the development of cells within the human body. Notch signaling pathways can determine how cells proliferate or change during development, and defects ...
Biochemistry
Sep 29, 2015
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67
Researchers at UCLA's Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research have discovered a mechanism by which certain adult stem cells suppress their ability to initiate skin cancer during their dormant ...
Cell & Microbiology
Dec 20, 2013
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The metabolism of lung cancer patients is different than the metabolism of healthy people. And so the molecules that make up cancer patients' exhaled breath are different too. A new device pioneered at the University of Colorado ...
Bio & Medicine
Nov 17, 2011
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Head and neck cancer, the sixth most common cancer in the world, has remained one of the more difficult malignancies to treat, and even when treatment is successful, patients suffer severely from the available therapies. ...
Bio & Medicine
Jul 15, 2011
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Most skin cancers are highly curable, but require surgery that can be painful and scarring.
Biochemistry
Jan 15, 2010
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A pair of researchers from the University of Delaware Department of Medical and Molecular Sciences are investigating genetic variations in DNA replication of human papillomaviruses (HPV) and its correlation with HPV-related ...
Biochemistry
May 23, 2018
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(HealthDay)—Cancer rates in dogs are about the same as in people, but there are far fewer drug treatments specifically targeted for dogs.
Plants & Animals
Sep 5, 2014
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Mayo Clinic researchers have shown that a molecule called Cul4 helps to deposit DNA-packaging histone proteins onto DNA, an integral step in cramming yards of genetic code into compact coils that can fit into each cell. When ...
Cell & Microbiology
Nov 7, 2013
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Researchers at The Pennsylvania State University College of Medicine, Hershey, Pennsylvania have discovered that the Opioid Growth Factor (OGF, [Met5]-enkephalin) and its receptor, OGFr, a clinically important system with ...
Cell & Microbiology
Aug 23, 2010
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