The good, the bad and the spliceosome

The Fas protein can either inhibit or promote the controlled cell death (apoptosis), depending on the isoform in which it occurs. Together with international colleagues, researchers from the Helmholtz Zentrum München and ...

How RNA could keep us young

With over 75 million baby boomers in the U.S. alone, age-related diseases are a major concern in the health care system. The connection between aging and cancer has become a pillar in medicine: we know that as we age, our ...

Scientists deconstruct one of the myths of biological innovation

While the number of coding genes that produce proteins in humans has dwindled to 20,000 in recent years, scientists think that the dimensions of the proteome could be larger. This diversity of proteins has become one of the ...

Researchers expose 'hidden layers' in fungi

If we are to tame fungi and optimize their extremely important role in our ecosystem, we must gain a more complete view of their functional abilities. Researchers from TU Delft and Utrecht University have exposed a previously ...

The RNA that snips and stitches RNA

RNA is a fundamental molecule that codes for protein and controls gene expression, playing a part in regulating many cell responses and vital processes. The genetic information contained in premature messenger RNA (mRNA), ...

Scientists find new roles for old RNAs

An international team of researchers has discovered unexpected functions of small nucleolar RNAs (snoRNAs) that explains the cause of some diseases. The research, led by Prof. Stefan Stamm from the University of Kentucky ...

Protein recipe requires precise timing

The activation of genes is a complicated biochemical endeavor akin to cooking a meal, and a new Yale study details just how precisely choreographed those steps need to be.

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