How human eggs end up with the wrong number of chromosomes

One day before ovulation, human oocytes begin to divide into what will become mature eggs. Ideally, eggs are packaged with a complete set of 23 chromosomes, but the process is prone to error, especially with age. In a Review ...

Success in the development of a gamma-tubulin specific inhibitor

Microtubules, one component of a cell's skeleton, are hollow tubes formed from the polymerization of α- and β-tubulin, which are themselves important structural proteins of the mitotic spindle that equally separates chromosomes ...

Molecular motor grows cell's microtubules

Motor proteins that pause at the ends of microtubules and produce pushing forces can also stimulate their growth, according to researchers at Penn State. The proteins' function could be a critical component in understanding ...

Decoding cell division's mysterious spindle matrix

Every high school biology class learns about the tiny cells that comprise our bodies, as well as about many of the diverse actions that they perform. One of these actions is called mitosis, the series of steps through which ...

New technique reveals a role for histones in cell division

(Phys.org) —Proteins known as histones give structure to DNA, which coils around them like string on spools. But as is so often the case in biology, it turns out there is more to these structures than meets the eye. Scientists ...

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