The Spatial Mouse Atlas: New insights into cell fate

High-resolution gene expression maps have been combined with single-cell genomics data to create a new resource for studying how cells adopt different identities during mammalian development. The Spatial Mouse Atlas is the ...

Reverse engineering 3-D chromosome models for individual cells

Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes—the highly complex, three-dimensional ...

Machine learning peeks into nano-aquariums

In the nanoworld, tiny particles such as proteins appear to dance as they transform and assemble to perform various tasks while suspended in a liquid. Recently developed methods have made it possible to watch and record these ...

3-D maps of gene activity

A three-dimensional computer model enables scientists to quickly determine which genes are active in which cells, and their precise location within an organ. A team led by Nikolaus Rajewsky, Berlin, and Nir Friedman, Jerusalem, ...

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