Researchers probe cell division defects to gain insight into cancer

From bugs to plants to animals, for all living things to grow they must create more cells. To do so, each existing cell, whether in an embryo or an adult, receives cues to copy its chromosomes—large pieces of DNA that contain ...

Turning silenced cancer genes back into fighters

Working with human colon cancer cells and mice, researchers led by experts at the Johns Hopkins Kimmel Cancer Center say they have successfully blocked the activity of portions of a protein known as UHRF1 and restored the ...

Nanoparticles give immune cells a boost

Programming the body's immune system to attack cancer cells has had promising results for treating blood cancers such as lymphoma and leukemia. This tactic has proven more challenging for solid tumors such as breast or lung ...

Why cancer drugs can't take the pressure

A major reason why cancer drugs fail is that they cannot penetrate the high-pressure environment of solid tumors. A study published May 10th in Biophysical Journal reveals that a large, naturally occurring molecule called ...

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