Using nature for inspiration, a team of Northwestern University scientists is the first to develop an entirely artificial molecular pump, in which molecules pump other molecules. This tiny machine is no small feat. The pump ...
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. ...
Like vast international trading companies, biological systems pick up freight items (in the form of small molecules), transport them from place to place and release them at their proper destination. These ubiquitous processes ...
Howard Hughes Medical Institute scientists have simplified the chemical synthesis of small molecules, eliminating a major bottleneck that limits the exploration of a class of compounds offering tremendous potential for medicine ...
One of the most exciting scientific advances made in recent years is CRISPR—the ability to precisely edit the genome of cells. However, although this method has incredible potential, the process is extremely inefficient. ...
Second messengers are small molecules that transmit signals in the cell. A single second messenger typically interacts with several signalling proteins. "Even though this may give the impression of promiscuity, the interactions ...
Researchers hypothesize that targeting components of the mammalian clock with small molecules like REV-ERB drugs may lead to new treatments for sleep disorders and anxiety disorders. It also is possible that REV-ERB drugs ...
A walking molecule, so small that it cannot be observed directly with a microscope, has been recorded taking its first nanometre-sized steps.
The resolution of scanning tunnelling microscopes can be improved dramatically by attaching small molecules or atoms to their tip. The resulting images were the first to show the geometric structure of molecules and have ...
Chemists have developed a revolutionary new way to manufacture natural chemicals and used it to assemble a scarce anti-inflammatory drug with potential to treat cancer and malaria.
May 19, 2015
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