Novel system reveals mechanisms of pluripotency transition

In a study published online in Nature Cell Biology on May 11, scientists from Guangzhou Institute of Biomedicine and Health (GIBH) of the Chinese Academy of Sciences established a novel and efficient system for non-integrated ...

Tracking life's first step: Two molecules 'awaken' brand new genome

Within hours after fertilization, a unique genome forms from chromosomes contributed by the egg and sperm. However, this new genome is initially inactive and must be "awakened" to begin the transcription of its DNA and start ...

The first potent COQ8 inhibitor targets ubiquinone biosynthesis

A new collaborative study from the University of Eastern Finland, Washington University in St. Louis, University of Wisconsin–Madison, University of North Carolina at Chapel Hill and the Promega Corporation discloses the ...

Growing blood stem cells in the lab to save lives

Hematopoietic stem cells (HSCs) are important immature blood cells in bone marrow that can be triggered to develop into any blood cell type. HSC transplants can be used to treat conditions where bone marrow is damaged and ...

Study identifies new mechanisms driving genomic instability

A recent Northwestern Medicine study published in the Journal of Cell Biology has identified new mechanisms that cause genomic or chromosomal instability during cell division, findings that may improve the development of ...

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