Related topics: protein · cells · cancer cells · genes · breast cancer

Learning from experience is all in the timing

As animals explore their environment, they learn to master it. By discovering what sounds tend to precede predatorial attack, for example, or what smells predict dinner, they develop a kind of biological clairvoyance—a ...

Using a promiscuous inhibitor to uncover cancer drug targets

Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.

Researchers uncover mechanism behind DNA damage control

DNA damage is occurring in our cells all the time due to external agents, such as exposure to sun, or internal agents, like reactive oxygen species. To detect and repair DNA lesions, cells have evolved DNA damage response. ...

How bird feather patterns form

Feathers evolved in dinosaurs and are a key characteristic of birds today. They are arranged in a precise hexagonal pattern in a bird's skin, but it has been unclear how this happens. According to a new study published February ...

How plants learned to save water

Tiny pores on the leaves of plants, called stomata, have a huge influence on the state of our planet. Through the stomata, plants absorb carbon dioxide, which is incorporated into carbohydrates, and release oxygen. But they ...

When a fish becomes fluid

Zebrafish aren't just surrounded by liquid, but turn liquid—in part—during their development. As the zebrafish embryo develops from a ball of cells to a fully-formed fish, a region of the embryo switches its phase from ...

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Signal transduction

In biology, 'signal transduction' refers to any process by which a cell converts one kind of signal or stimulus into another. Most processes of signal transduction involve ordered sequences of biochemical reactions inside the cell, which are carried out by enzymes and activated by second messengers, resulting in a signal transduction pathway. Such processes are usually rapid, lasting on the order of milliseconds in the case of ion flux, or minutes for the activation of protein- and lipid-mediated kinase cascades, but some can take hours, and even days (as is the case with gene expression), to complete. The number of proteins and other molecules participating in the events involving signal transduction increases as the process emanates from the initial stimulus, resulting in a "signal cascade," beginning with a relatively small stimulus that elicits a large response. This is referred to as amplification of the signal.

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