DNA nanostructures for targeting cellular surface receptors

A broad subset of parameters, which include cell signaling modulation and receptor binding efficiency, can be explored using programmable DNA nanostructures. Glenn Cremers shows how these structures can uncover important ...

Cell biology: How mitochondria report stress

Ludwig Maximilian University of Munich researchers have discovered the mechanism by which the protein DELE1 detects organelle stress. This offers a possible new approach for treating neurodegenerative diseases.

How bacteria cope with stress

When exposed to stress, bacteria allow their metabolism to take a break during which they suppress, for example, the incorporation of proteins into membranes. Scientists from Marburg, Freiburg and Munich have discovered this ...

Hunting for human obesity genes in fat fruit flies

Fruit flies provide an effective platform for screening new obesity genes, and fat flies implicate a neuronal signaling pathway in weight gain, according to a new study publishing November 4th in the open-access journal PLOS ...

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