Researchers have used a highly precise genome-editing technology called base editing to make hundreds of direct edits to blood stem cells from patients' bone marrow.
Cell & Microbiology
May 3, 2023
0
11
Researchers at the University of Zurich have developed a new tool that uses artificial intelligence to predict the efficacy of various genome-editing repair options. Unintentional errors in the correction of DNA mutations ...
Biotechnology
Feb 2, 2023
0
46
A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.
Cell & Microbiology
Oct 24, 2022
0
23
Red blood cells are the most abundant cell type in blood, carrying oxygen throughout the human body. In blood circulation, they repetitively encounter various levels of oxygen tension. Hypoxia, a low oxygen tension condition, ...
Biochemistry
Sep 21, 2021
0
108
Keck Graduate Institute (KGI) Assistant Professor and University of California, Berkeley Visiting Scientist Dr. Kiana Aran first introduced the CRISPR-Chip technology in 2019. Now just two years later, she has expanded on ...
Biotechnology
Apr 5, 2021
0
148
In a new study by the Yale Department of Immunobiology and Yale Cancer Center, researchers report combined liver and growth factor humanization enhances human red blood cell production and survival in circulation the immunodeficient ...
Cell & Microbiology
Mar 5, 2021
0
44
Scientists have developed an affordable, downloadable app that scans for potential unintended mistakes when CRISPR is used to repair mutations that cause disease. The app reveals potentially risky DNA alterations that could ...
Biotechnology
Feb 11, 2021
0
478
Scientists at St. Jude Children's Research Hospital have developed an easy to use, sensitive and high-throughput method to define sites of unintended double stranded breaks in DNA caused by genome editors like the CRISPR-Cas9 ...
Biotechnology
Jun 16, 2020
0
18
Amidst rising hopes for using CRISPR gene editing tools to repair deadly mutations linked to conditions like cystic fibrosis and sickle cell disease, a study in Communications Biology describes a new innovation that could ...
Biotechnology
Dec 6, 2019
0
199
City of Hope researchers may have found a way to sharpen the fastest, cheapest and most accurate gene editing technique, CRISPR-Cas9, so that it can more successfully cut out undesirable genetic information.
Biotechnology
Nov 7, 2019
0
212
