Revealing the molecular mechanism of nucleolar RNA

A research group led by Prof. Guang Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. Feng Xuezhu from the First Affiliated Hospital of USTC, ...

A molecular hammock for cotranslational modification

Proteins do most of the real work in cells and are modified in accordance with functional requirements. An LMU team has now shown how proteins are chemically altered on the ribosome, even before they fold into the active ...

Pinpointing mutations that cause bacterial antibiotic resistance

Researchers in Japan have developed a new way of testing bacterial resistance to antibiotics, and found three previously unknown resistance mutations in the process. The fact that they detected both known and unknown mutations ...

Structural biology: Until the last cut

Ribosomes are the cell's protein factories. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have now structurally characterized late stages in the assembly of the human small ribosomal subunit, yielding detailed ...

Linking cytosolic and chloroplast ribosome biogenesis in plants

Scientists at Tokyo Institute of Technology (Tokyo Tech) have found that eukaryotic and bacterial growth regulation systems of independent origins are connected to the control of chloroplast rRNA transcription in a primitive ...

Preventing the spread of repression

Scientists at the Friedrich Miescher Institute for Biomedical Research have identified a novel and unexpected regulatory activity of RNA at the edge of inactive chromosomal regions. In their publication in Nature Structural ...

GI pathogen at lake linked to human fecal contamination

(HealthDay)—Water at beaches along Lake Erie contains a pathogen associated with human fecal contamination, Arcobacter species, which are known to cause gastrointestinal illness in humans, and levels correlate with beach ...

One secret to how TB sticks with you

Mycobacterium tuberculosis is arguably the world's most successful infectious agent because it knows how to avoid elimination by slowing its own growth to a crawl. Now, a report in the July 10 issue of the journal Cell, a ...

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