The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant type of RNA within cells, when resources are scarce and the bacteria Escherichia coli needs to slow ...
Biotechnology
Jan 22, 2021
0
21
RNA interference is a gene regulatory mechanism in which the expression of specific genes is downregulated by endogenous microRNAs or by small interfering RNAs (siRNAs). Although siRNAs have broad potential for gene-silencing ...
Molecular & Computational biology
Oct 16, 2020
0
3
In every cell, RNA-binding proteins (RBPs) help tune gene expression and control biological processes by binding to RNA sequences. Researchers often assume that individual RBPs latch tightly to just one RNA sequence. For ...
Molecular & Computational biology
Sep 9, 2020
0
45
ETH Zurich researchers can predict how tightly a cell's protein synthesis machinery will bind to RNA sequences—even when dealing with many billions of different RNA sequences. This binding plays a key role in determining ...
Molecular & Computational biology
Aug 27, 2020
0
53
Many viruses, including HIV and influenza A, mutate so quickly that identifying effective vaccines or treatments is like trying to hit a moving target. A better understanding of viral propagation and evolution in single cells ...
Biochemistry
Aug 20, 2020
0
175
An international team led by the Plant Phenotyping and Imaging Research Centre (P2IRC) at the University of Saskatchewan (USask) and researchers at Agriculture and Agri-Food Canada (AAFC) has decoded the full genome for the ...
Biotechnology
Aug 10, 2020
0
34
The human genome contains about 20,000 protein-coding genes, but the coding parts of our genes account for only about 2 percent of the entire genome. For the past two decades, scientists have been trying to find out what ...
Biotechnology
Jul 29, 2020
0
268
As cells develop, changes in how our genes interact determines their fate. Differences in these genetic interactions can make our cells robust to infection from viruses or make it possible for our immune cells to kill cancerous ...
Molecular & Computational biology
Jul 13, 2020
0
139
Single-cell RNA sequencing is a powerful tool for identifying transcriptomic variations and developmental trajectories in cell types that determine the course of diseases like cancer, with the goal of eventually improving ...
Molecular & Computational biology
Jun 22, 2020
0
4
A typo appearing in the draft of a novel is no great calamity. Nature, however, is often less forgiving of errors. A change in just one letter of the genetic code can have catastrophic consequences for human health.
Biotechnology
Feb 27, 2020
0
15
