Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.
Molecular & Computational biology
Sep 6, 2021
0
99
The corona pandemic has ensured that the term "mRNA" is now also known to a large public beyond laboratories and lecture halls. However, the molecule is much more than an important component of a successful vaccine against ...
Molecular & Computational biology
Jul 14, 2021
0
8
If the genome is the recipe of life, base pairs are the individual ingredients listed. These chemical structures form DNA, and every living organism on Earth has just four. The specific arrangements of these four base pairs—A, ...
Cell & Microbiology
Jun 17, 2021
0
2023
Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same class of machines, called polymerases, also build RNA messages, which are like notes copied from the central DNA repository ...
Molecular & Computational biology
Jun 11, 2021
39
12351
A bacterial protein helps to stop transcription—the process of making RNA copies of DNA to carry out the functions of the cell—by causing the cellular machinery that transcribes the DNA to pause at the appropriate spots ...
Biotechnology
May 7, 2021
0
82
A group of researchers at the Hong Kong University of Science and Technology (HKUST) has uncovered the mechanism of how DNA is being melted to start bacterial gene transcription and how one class of antibiotics inhibits this ...
Cell & Microbiology
May 5, 2021
0
22
To better understand how RNA in bacteria gives rise to protein—and along the way, target these processes in the design of new antibiotics—researchers are turning their attention to the unique way this process happens ...
Molecular & Computational biology
Apr 14, 2021
0
210
Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 ...
Cell & Microbiology
Apr 7, 2021
0
139
How did life begin on Earth and could it exist elsewhere? Researchers at Simon Fraser University have isolated a genetic clue—an enzyme known as an RNA polymerase—that provides new insights about the origins of life. ...
Evolution
Mar 19, 2021
25
6444
An international team of scientists from the University of Turku, Finland and PennState University, U.S. have solved a long-standing mystery of how living organisms distinguish RNA and DNA building blocks during gene expression ...
Biotechnology
Mar 17, 2021
0
18
