Related topics: gene expression

Regulating the ribosomal RNA production line

The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant type of RNA within cells, when resources are scarce and the bacteria Escherichia coli needs to slow ...

Integrator: A guardian of the human transcriptome

In a joint collaboration, Danish and German researchers have characterized a cellular activity that protects our cells from potentially toxic by-products of gene expression. This activity is central for the ability of multicellular ...

RNA molecules are masters of their own destiny

At any given moment in the human body, in about 30 trillion cells, DNA is being "read" into molecules of messenger RNA, the intermediary step between DNA and proteins, in a process called transcription.

Quick and sensitive identification of multidrug-resistant germs

Researchers from the University of Basel have developed a sensitive testing system that allows the rapid and reliable detection of resistance in bacteria. The system is based on tiny, functionalized cantilevers that bend ...

Gut microbiome manipulation could result from virus discovery

Scientists have discovered how a common virus in the human gut infects and takes over bacterial cells—a finding that could be used to control the composition of the gut microbiome, which is important for human health.

RNA information transfer could be used in repairing DNA

Genomes are routinely subjected to DNA damage. But most cells have DNA repair systems that enforce genome stability and, ideally, prevent diseases like cancer. The trouble gets serious when these systems break down. When ...

Scientists discover new rules about 'runaway' transcription

On the evolutionary tree, humans diverged from yeast roughly 1 billion years ago. By comparison, two seemingly similar species of bacteria, Escherichia coli and Bacillus subtilis, have been evolving apart for roughly twice ...

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RNA polymerase

RNA polymerase (RNAP or RNApol) is an enzyme that produces RNA. In cells, RNAP is needed for constructing RNA chains from DNA genes as templates, a process called transcription. RNA polymerase enzymes are essential to life and are found in all organisms and many viruses. In chemical terms, RNAP is a nucleotidyl transferase that polymerizes ribonucleotides at the 3' end of an RNA transcript.

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