UT Southwestern researchers have identified a four-protein complex that appears to play a key role in generating ribosomes—organelles that serve as protein factories for cells—as well as a surprising part in neurodevelopmental ...
Cell & Microbiology
Mar 29, 2022
0
99
As a molecular machine found in the cells of all organisms, the ribosome is responsible for making new proteins. It reads the blueprint for a certain protein on a messenger molecule—known as messenger RNA (mRNA)—and then ...
Molecular & Computational biology
Mar 14, 2022
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191
The knobby, 3D structure on the screen in front of Rachel Green showed an intracellular car wreck never before seen by scientists. It also confirmed a hypothesis a team in her lab had been working on for months.
Molecular & Computational biology
Mar 9, 2022
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89
Researchers solve the more than 25-year-old puzzle of how proteins are sorted in the cell. A protein complex known as NAC (nascent polypeptide-associated complex) serves as a "gatekeeper" in protein synthesis, regulating ...
Cell & Microbiology
Feb 24, 2022
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91
The vast majority of biological processes rely on proteins to carry out various jobs in all living cells, including neurons, which transmit information throughout the nervous system.
Cell & Microbiology
Feb 3, 2022
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36
Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein ...
Molecular & Computational biology
Jan 19, 2022
0
73
Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists at Tokyo Institute of ...
Cell & Microbiology
Nov 15, 2021
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26
A new study published in Nature Communications sheds light on the molecular function of one of the enzymes with RNA helicase activity involved in the synthesis process of the large ribosome subunit. By combining biochemical, ...
Molecular & Computational biology
Nov 3, 2021
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6
All proteins in a cell are assembled by complicated molecular machines. The precursors of these ribosomes are produced in the cell nucleus and then enter the cell through the so-called nuclear pores. Researchers at the University ...
Cell & Microbiology
Oct 27, 2021
1
2505
A research group led by Prof. Guang Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. Feng Xuezhu from the First Affiliated Hospital of USTC, ...
Molecular & Computational biology
Sep 27, 2021
0
6
