A solid scaffolding for cells

To perform the task for which they have been synthesized, proteins must first assemble to form effective cellular "machines." But how do they recognize their partners at the right time? Researchers at the University of Geneva ...

A molecular hammock for cotranslational modification

Proteins do most of the real work in cells and are modified in accordance with functional requirements. An LMU team has now shown how proteins are chemically altered on the ribosome, even before they fold into the active ...

Scientists study genes misidentified as 'non-protein coding'

The human genome contains regions that "code" for proteins, which means they have instructions to make protein molecules with specific functions in the body. But Yale researchers have discovered several protein-coding genes ...

Revisiting the hub of protein synthesis

Proteins are not only necessary for making strong muscles, they are also required for establish new connections between neurons during the learning process. A defect in protein synthesis leads to defects in learning, memory ...

How protein complexes form in the cell

The formation of protein complexes is a highly organised process that does not begin with the "finished" proteins. Studies conducted by researchers at the Center for Molecular Biology of Heidelberg University (ZMBH) and the ...

Tiny protein has big impact in times of stress

Ribosomes churn out proteins that carry out all of life's functions, but when missing a key and previously overlooked factor, they can break down in times of stress, Yale University scientists have discovered. 

A very special protein synthesis machinery

Sleeping sickness-causing parasites contain an unusual protein synthesis mechanism. A team of researchers from ETH Zurich and the University of Bern have resolved its very special structure for the first time. Ribosomes are ...

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