Researchers create bioluminescent tag to detect DNA break repair

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan. The international team's ...

Scientists discover body's protection shield

Scientists have discovered a way to manipulate the body's own immune response to boost tissue repair. The findings, published in Current Biology today, reveal a new network of protective factors to shield cells against damage. ...

Study tracks evolutionary history of metabolic networks

By analyzing how metabolic enzymes are built and organized, researchers have reconstructed the evolutionary history of metabolism. Their study shows how metabolic networks—which drive every cellular process from protein ...

CRISPR-based tool maps gene function in human cells

UC San Francisco scientists have used a high-throughput CRISPR-based technique to rapidly map the functions of nearly 500 genes in human cells, many of them never before studied in detail.

Plants fix DNA differently from animals

In mammalian cells, the transcription factor p53 most responsible for healthy growth of the organism. The equivalent in plants is Suppressor Of Gamma Response 1 (SOG1), a factor that does not share a common evolutionary ancestor ...

The right way to repair DNA

Is it better to do a task quickly and make mistakes, or to do it slowly but perfectly? When it comes to deciding how to fix breaks in DNA, cells face the same choice between two major repair pathways. The decision matters, ...

A new path to fixing genes in living organisms

A unique gene-editing method that efficiently inserts DNA into genes located in dividing and non-dividing cells of living rats has been developed by a team of international researchers, including scientists from KAUST.

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