New method to detect off-target effects of CRISPR

Since the CRISPR genome editing technology was invented in 2012, it has shown great promise to treat a number of intractable diseases. However, scientists have struggled to identify potential off-target effects in therapeutically ...

More than 20-year-old assumption about beer aroma disproved

Hops-derived constituents not only increase shelf-life and bitterness of beer, but can also significantly influence aroma. An important hop odorant is linalool, which has a floral and citrus-like scent.

Nanocontainers introduced into the nucleus of living cells

An interdisciplinary team from the University of Basel in Switzerland has succeeded in creating a direct path for artificial nanocontainers to enter into the nucleus of living cells. To this end, they produced biocompatible ...

New technology will show how RNA regulates gene activity

The discovery of a huge number of long non-protein coding RNAs, aka lncRNAs, in the mammalian genome was a major surprise of the recent large-scale genomics projects. An international team including a bioinformatician from ...

A numerical protocol to estimate local entropy production

In physics, equilibrium is a state in which a system's motion and internal energy do not change over time. Videos of systems in equilibrium would look exactly the same if they were watched in their normal chronological progression ...

Robot car to cut jams & prangs

Robotic car technology being developed at Oxford University that interprets its surroundings and makes decisions about where to go could eliminate the agony and cost of traffic jams.

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