The mammalian cerebellum has long been associated almost exclusively with motor control, yet recent studies indicate that it also contributes to many higher brain functions. An international research team led by Prof. Dr. ...
Molecular & Computational biology
Jul 30, 2021
0
197
Proteins known as transcription factors act as switches that regulate the expression of nearby genes, but the identity of some of these genetic levers has so far remained mysterious. Now, researchers from the Schübeler group ...
Biotechnology
Jul 8, 2021
0
30
Scientists know that developing cells in a healthy embryo will transform into a variety of cell types that will make up the different organ systems in the human body, a process known as cell differentiation. But they don't ...
Cell & Microbiology
Jun 14, 2021
0
11
With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar. Understanding the biological features that make us human is part of a fascinating and intensely debated line of research. Researchers ...
Evolution
Dec 16, 2020
0
467
A team of biomedical engineers at Duke University has created a new way to turn stem cells into a desired cell type by mastering the language of gene regulatory networks.
Biotechnology
Dec 1, 2020
0
29
As the world scrambles to control the growing COVID-19 coronavirus pandemic, new research in Nature Structural & Molecular Biology shows viruses also play a key evolutionary role in mammals' ability to reproduce and survive.
Molecular & Computational biology
Sep 7, 2020
1
281
The genes regulating pluripotent stem cells in mammals are surprisingly similar across 48 species, Kyoto University researchers report in the journal Genome Biology and Evolution. The study also shows that differences among ...
Evolution
Sep 7, 2020
0
88
Scientists around the world have access to a rich trove of information through the Encyclopedia of DNA Elements (ENCODE)—annotated versions of the human and mouse genomes that are vital for interpreting their genetic codes. ...
Biotechnology
Jul 29, 2020
0
16
A key epigenetic mark can block the binding of an important gene regulatory protein, and therefore prohibit the gene from being turned off, a new UNSW study in CRISPR-modified mice—published this month in Nature Communications—has ...
Biotechnology
May 25, 2020
0
380
Disruption of certain DNA structures—called topologically associating domains, or TADs—is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps ...
Biotechnology
Dec 17, 2019
0
215
