Although the knowledge we have about human cells and tissues has steadily increased over recent decades, many things remain unknown. For instance, cells exist in transient, dynamic states and understanding them is fundamental ...
Cell & Microbiology
Jun 4, 2019
0
4
How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...
Molecular & Computational biology
May 2, 2019
0
91
Snakes and lizards are reptiles that belong to the order Squamata. They share several traits but differ in one obvious respect: Snakes do not have limbs. The two suborders diverged more than 100 million years ago. Identification ...
Evolution
Feb 7, 2019
11
273
Researchers from the Department of Genetics, Microbiology and Statistics and the Institute of Biomedicine of the University of Barcelona (UB), in collaboration with the Centre for Genomic Regulation (CRG), have described ...
Biotechnology
Dec 5, 2018
0
6
Technological advances have enabled scientists to obtain massive amounts of data on different information-carrying molecules in cells and tissues, such as DNA, proteins and various forms of RNA. However, to date, it has been ...
Molecular & Computational biology
Nov 8, 2018
0
1
It was long thought that DNA, together with the genes encoded in it, determined genetic destiny. But equally important is coordinating when genes are turned on and off. In fact, the regulation of gene expression defines life ...
Evolution
Sep 11, 2018
1
15
The sites where transcription factors bind within regulatory DNA fall into six distinct patterns that overlap with the factors' functions, Broad scientists find, helping advance a goal of regulatory genomics.
Cell & Microbiology
Jul 11, 2018
0
7
In recent years, it has become evident that the spatial organisation of the genome is key for its function. This depends on a number of factors, including the cohesin protein complex. This essential complex is present in ...
Cell & Microbiology
Jun 5, 2018
0
62
A team of biologists and computer scientists has adopted a time-based machine-learning approach to deduce the temporal logic of nitrogen signaling in plants from genome-wide expression data. The work potentially offers new ...
Biotechnology
May 14, 2018
0
80
Flowering plants have evolved from plants without flowers. It is known that the function of several genes, called MADS-box genes, creates shapes peculiar to flowers such as stamens, pistils and petals. Plants that do not ...
Biotechnology
Jan 11, 2018
0
16
