How genes interact to build tissues and organisms

Although the knowledge we have about human cells and tissues has steadily increased over recent decades, many things remain unknown. For instance, cells exist in transient, dynamic states and understanding them is fundamental ...

A model to decipher the complexity of gene regulation

How, where and when genes are expressed determine individual phenotypes. If gene expression is controlled by many regulatory elements, what, ultimately, controls them? And how does genetic variation affect them? The SysGenetiX ...

Research explains how snakes lost their limbs

Snakes and lizards are reptiles that belong to the order Squamata. They share several traits but differ in one obvious respect: Snakes do not have limbs. The two suborders diverged more than 100 million years ago. Identification ...

Can you evolve while being robust?

It was long thought that DNA, together with the genes encoded in it, determined genetic destiny. But equally important is coordinating when genes are turned on and off. In fact, the regulation of gene expression defines life ...

The origin of flower-making genes

Flowering plants have evolved from plants without flowers. It is known that the function of several genes, called MADS-box genes, creates shapes peculiar to flowers such as stamens, pistils and petals. Plants that do not ...

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