A powerful new way of analysing how drugs interact with molecules in the body could aid the design of better treatments with fewer side-effects.
Biochemistry
Oct 5, 2017
0
81
With the heightened concerns over the dangerous side effects of the once-popular antidiabetic drug Avandia, researchers at The Scripps Research Institute (TSRI) in Jupiter, Florida, are working to understand how small molecules, ...
Biochemistry
Sep 30, 2017
0
93
G protein-coupled receptors are the key target of a large number of drugs. Würzburg scientists have now been able to show more precisely how these receptors act in the cell interior.
Biochemistry
Sep 5, 2017
0
7
A team spearheaded by Van Andel Research Institute scientists has answered a long-standing question that may lead to more effective drugs with fewer side effects for diseases ranging from heart failure to cancer.
Biochemistry
Jul 27, 2017
0
94
Glutamate receptors play a central role in the human nervous system. Scientists estimate 90 percent of the human brain's synapses, or connections between neurons, send signals using glutamate. The role of similar receptors ...
Cell & Microbiology
Jul 24, 2017
0
11
As senses go, there's nothing so immediate and concrete as our sense of touch. So it may come as a surprise that, on the molecular level, our sense of touch is still poorly understood.
Cell & Microbiology
Jul 4, 2017
0
266
Researchers at the University of Michigan, Stanford University and biotech company ConfometRx have captured the first cryo-electron microscopy snapshots of a key cellular receptor in action.
Biochemistry
May 24, 2017
2
8
Nematodes are a huge threat to agriculture since they parasitize important crops such as wheat, soybean, and banana; but plants can defend themselves. Researchers at Bonn University, together with collaborators from the Sainsbury ...
Biotechnology
Apr 13, 2017
0
3
An international team including researchers from MIPT's Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of how bacteria process external signals. By identifying the detailed structure of ...
Cell & Microbiology
Apr 10, 2017
0
196
Researchers hope to design a new generation of drugs against an array of deadly diseases. The task, however, is costly, arduous and often ineffective. One of the key challenges is understanding a particular class of proteins ...
Biochemistry
Apr 5, 2017
0
109
