Using a broad spectrum of analytical tools, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a class of novel compounds that can alter cell signaling activity, resulting in a variety ...
Biochemistry
Mar 26, 2013
1
0
Substances known as transcription factors often determine how a cell develops as well as which proteins it produces and in what quantities. Transcription factors bind to a section of DNA and control how strongly a gene in ...
Cell & Microbiology
Sep 2, 2016
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105
Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, ...
Biochemistry
Dec 29, 2016
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271
Class B G protein-coupled receptors (GPCRs) exert essential action in hormonal homeostasis and are important therapeutic targets for a variety of diseases including metabolic disorders such as type 2 diabetes. These receptors ...
Biochemistry
Jan 4, 2018
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162
Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many ...
Biochemistry
Aug 20, 2014
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0
EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...
Biochemistry
Dec 2, 2019
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36
Researchers have engineered an artificial protein that may block malignant properties of cancer cells as well as correct certain birth defects.
Biochemistry
Nov 14, 2017
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27
(Phys.org)—Epigenetics - the science of how gene activity can be altered without changes in the genetic code - plays a critical role in every aspect of life, from the differentiation of stem cells to the regulation of metabolism ...
Biotechnology
Jan 8, 2013
1
0
For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain ...
Cell & Microbiology
Jun 30, 2020
0
265
New collaborative research from Northwestern University and Lund University may have people heading to their backyard instead of the store at the outset of this year's mosquito season.
Plants & Animals
Mar 4, 2021
1
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