Bacterial colonization of the lung also depends on the host genome

The lung is by no means a sterile place, as was assumed for a long time. In fact, it actually harbors a diverse microbial ecosystem. We know from previous studies that changes in the lung microbiome are associated with diseases ...

How cells are influenced by their environment as tissues grow

How does an embryo develop? How do children grow, wounds heal or cancer spread? All of this has to do with the growth of body tissue. One of the major research interests of ETH Professor Viola Vogel and her senior assistant ...

Moonlighting protein makes a hospital germ harmful

The Pseudomonas aeruginosa bacterium is a widespread and dangerous hospital germ. It infects the respiratory tract and lungs and possesses natural resistance to numerous antibiotics. There is an ongoing search for so-called ...

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Interstitial lung disease

Interstitial lung disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). It concerns alveolar epithelium, pulmonary capillary endothelium, basement membrane, perivascular and perilymphatic tissues.

The term ILD is used to distinguish these diseases from obstructive airways diseases.

Most types of ILD involve fibrosis, but this is not essential. The term "pulmonary fibrosis" is no longer considered a synonym. Idiopathic pulmonary fibrosis is one form of "interstitial lung disease".

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