New lung 'organoids' in a dish mimic features of full-size lung

New lung "organoids"—tiny 3-D structures that mimic features of a full-sized lung—have been created from human pluripotent stem cells by researchers at Columbia University Medical Center (CUMC). The team used the organoids ...

Team develops targeted drug delivery to lung

Researchers from Columbia Engineering and Columbia University Medical Center (CUMC) have developed a new method that can target delivery of very small volumes of drugs into the lung. Their approach, in which micro-liters ...

Study of stem cell diseases advanced by new technique

A rare genetic disease called dyskeratosis congenita, caused by the rapid shortening of telomeres (protective caps on the ends of chromosomes), can be mimicked through the study of undifferentiated induced pluripotent stem ...

Pulmonary fibrosis inhibited by pentraxin-2/SAP in research study

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the International Journal of Biochemistry ...

Placenta-derived stem cells may help sufferers of lung diseases

An Italian research team, publishing in the current issue of Cell Transplantation (18:4), has found that stem cells derived from human placenta may ultimately play a role in the treatment of lung diseases, such as pulmonary ...

Interstitial lung disease

Interstitial lung disease (ILD), also known as diffuse parenchymal lung disease (DPLD), refers to a group of lung diseases affecting the interstitium (the tissue and space around the air sacs of the lungs). It concerns alveolar epithelium, pulmonary capillary endothelium, basement membrane, perivascular and perilymphatic tissues.

The term ILD is used to distinguish these diseases from obstructive airways diseases.

Most types of ILD involve fibrosis, but this is not essential. The term "pulmonary fibrosis" is no longer considered a synonym. Idiopathic pulmonary fibrosis is one form of "interstitial lung disease".

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