Further insights into the SARS-CoV-2 spike protein glycan shield

An unprecedented wealth of information has been gathered on SARS-CoV-2 in a very short period. This information is primarily focused on the cellular entry process and mechanism of antibody recognition where mainly protein-protein ...

Uncovering warped protein interactions in cancer

Scientists at Emory have revealed widespread distortions of a cell's protein interaction machinery resulting from cancer-causing mutations. They developed a process resembling ground-penetrating radar, for its ability to ...

New advances in protein-folding process thermodynamics

In biophysics, the kinetic states of molecules play a determining role in the metabolic and physiological processes in which they take part. Now, a paper published in the journal Proceedings of the National Academy of Sciences ...

Probing how proteins pair up inside cells

Despite its minute size, a single cell contains billions of molecules that bustle around and bind to one another, carrying out vital functions. The human genome encodes about 20,000 proteins, most of which interact with partner ...

Deadly combination: New direct trigger for cell death discovered

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay ...

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