A study has solved a long-standing debate about the transport of essential proteins, implicated in many human diseases, through one of the cell's most complex and sophisticated structures.
Molecular & Computational biology
May 4, 2020
0
255
The human glutamine transporter ASCT2 is upregulated in several forms of cancer. It is also the docking platform for a wide range of pathogenic retroviruses. A team of University of Groningen scientists have used cryo-electron ...
Biochemistry
Jun 6, 2018
0
767
(Phys.org) —Growing concern about bacterial resistance to existing antibiotics has created strong interest in new approaches for therapeutics able to battle infections. The work of an international team of researchers that ...
Cell & Microbiology
Sep 9, 2013
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0
(PhysOrg.com) -- Understanding how plants produce storage organs that humans use as food would be a valuable tool for science and for a hungry world.
Plants & Animals
Mar 3, 2009
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0
Based on genetic blueprints, individual amino acids are assembled into long amino acid chains, the proteins, in the protein factories of our cells, the ribosomes. Each newly formed protein starts with the amino acid methionine. ...
Cell & Microbiology
Jun 22, 2023
0
61
Scientists at the University of Groningen have constructed synthetic vesicles in which ATP, the main energy carrier in living cells, is produced. The vesicles use the ATP to maintain their volume and their ionic strength ...
Biotechnology
Sep 18, 2019
0
994
(PhysOrg.com) -- A study to be published as the "Paper of the Week" in the Journal of Biological Chemistry this December details how zinc, an element fundamental to cell growth, enters the cell via zinc-specific uptake proteins. ...
Biochemistry
Nov 22, 2010
0
0
It's not just humans and animals that suffer when the mercury rises, plants feel the heat too. Heat stress is a major issue in agriculture and can significantly reduce crop yield. Even small increases in temperature can affect ...
Biotechnology
Feb 13, 2018
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113
The current global epidemic of obesity-linked diabetes and its associated consequences -cardiovascular, neurological and renal diseases - is a growing public health problem for which therapeutic options are limited.
Biochemistry
Oct 22, 2013
0
0
The group of Prof. Dr. Ralf Erdmann at the Ruhr-Universität Bochum, Germany, discovered a connection of peroxisomal protein import and receptor export. In the Journal of Biological Chemistry, they disclosed that enzymes ...
Biochemistry
Feb 10, 2012
0
0
