New insights into a fundamental process in mitochondria

Researchers at Karolinska Institutet have uncovered the function of the release factor mtRF1 in the final steps of mitochondrial protein synthesis. The study, published in Nature Communications, reveals new insights into ...

Why synonymous mutations are not always silent

New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...

Efficient mRNA delivery by branched lipids

Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...

Gaining structural insight into the influenza virus

A team of scientists at University of Oxford have worked with multiple techniques at Diamond Light Source, to solve the structure of the influenza replication machinery and to determine how it interacts with cellular proteins. ...

Newly identified compound binds to Shiga toxin to reduce its toxicity

A strain of E. coli bacteria called enterohemorrhagic E. coli (EHEC) is known to cause several gastrointestinal disorders, which include bloody diarrhea and abdominal cramps, by damaging the intestinal lining. When accompanied ...

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