Solid-state NMR unveils fluoride ion channel permeation mechanism

A research team led by Shi Chaowei from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) has adapted the fluoride ion channel protein Fluc-Ec1 combined with deuterium substitution ...

New 'radar' detects active cellular destroyers

Cells in the human body must adapt their protein balance to certain situations, such as the availability of iron or an infection. These adaptations occur through a complex process in which proteins that are no longer needed ...

Neural network helps design brand new proteins

With their intricate arrangements and dynamic functionalities, proteins perform a plethora of biological tasks by employing unique arrangements of simple building blocks where geometry is key. Translating this nearly limitless ...

Deciphering the molecular dynamics of complex proteins

Which structures do complex proteins adopt in solution? Konstanz biophysicists answer this question using the example of ubiquitin dimers as well as a new combination of high-resolution NMR spectroscopy and sophisticated ...

New inhibitor for regulating the essential protein SMNDC1

The SMNDC1 gene controls key functions in the human body and is linked to diseases such as diabetes and cancer. Scientists in Stefan Kubicek's research group at the CeMM Research Center for Molecular Medicine of the Austrian ...

page 4 from 40