Six years ago, Michael Niederweis, Ph.D., described the first toxin ever found for the deadly pathogen Mycobacterium tuberculosis. This toxin, tuberculosis necrotizing toxin, or TNT, became the founding member of a novel ...
Molecular & Computational biology
Apr 8, 2021
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88
When bacteria such as Salmonella or Yersinia cause fever, diarrhoea or abdominal pain, tiny 'injection needles' are at work: their type 3 secretion system, or T3SS for short, shoots bacterial virulence proteins directly into ...
Cell & Microbiology
May 13, 2020
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61
An international team headed by Óscar Llorca at the Spanish National Cancer Research Centre (CNIO), and the group led by Sebastian Geibel at the University of Würzburg (Germany), report an accurate 3-D model of the mechanism ...
Biochemistry
Oct 9, 2019
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43
Researchers from the Massachusetts General Hospital (MGH) Division of Infectious Diseases are investigating the mechanism by which several important pathogenic species of bacteria deliver proteins into the cells of the organisms ...
Cell & Microbiology
Mar 9, 2016
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12
Every year, more strains of bacteria develop resistance to the antibiotics we use to treat deadly infections. At The Scripps Research Institute (TSRI) scientists have been working to develop new forms of these drugs, including ...
Cell & Microbiology
Aug 20, 2015
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83
Many pathogenic bacteria use special secretion systems to deliver toxic proteins into host cells. Researchers of Ludwig-Maximilians-Universitaet (LMU) in Munich have determined the structure of a crucial part of one of these ...
Cell & Microbiology
Jun 20, 2014
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0
(Phys.org)—It is much harder to keep up with a conversation in a crowded bar than in a quiet little café, but scientists wishing to eavesdrop on cells can now do so over the laboratory equivalent of a noisy room. A new ...
Biotechnology
Sep 24, 2012
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(Phys.org)—It's a battleground down there—in the soil where plants and bacteria dwell.
Biotechnology
Sep 21, 2012
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(Phys.org) -- An international collaboration between scientists in University College Dublin and the European Molecular Biology Laboratory (EMBL) has revealed for the first time that 15% of the proteins encoded by the human ...
Cell & Microbiology
Jun 4, 2012
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Insect glands are responsible for producing a host of secretions that allow bees to sting and ants to lay down trails to and from their nests. New research from Carnegie scientists focuses on secretions from glands in the ...
Plants & Animals
May 3, 2012
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