Scientists have determined the three-dimensional structure of a complete, unmodified G-protein-coupled receptor in its native environment: embedded in a membrane in physiological conditions.
Biochemistry
Oct 22, 2012
0
0
(PhysOrg.com) -- Researchers at Sandia National Laboratories have developed a super-resolution microscopy technique that is answering long-held questions about exactly how and why a cell's defenses fail against some invaders, ...
Analytical Chemistry
May 16, 2011
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0
Researchers from FOM institute AMOLF have discovered what determines the accuracy with which cells can measure chemical concentrations. They described the results of their research in two publications: on 24 November online ...
Biochemistry
Dec 16, 2014
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64
A group of researchers led by Prof. Arun K. Shukla in the Department of Biological Sciences and Bioengineering at the Indian Institute of Technology Kanpur (IIT-K) has unraveled a previously unknown mechanism that regulates ...
Cell & Microbiology
Jun 6, 2023
0
54
Researchers have discovered a new set of signals that cells send and receive to prompt one type of fat cell to convert fat into heat. The signaling pathway, discovered in mice, has potential implications for activating this ...
Cell & Microbiology
Jun 12, 2020
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215
The fight against antibiotic-resistant superbugs has taken a step forward thanks to a new discovery by scientists at The University of Nottingham.
Cell & Microbiology
Aug 13, 2013
1
0
(Phys.org) —A team of researchers with members from several facilities in California and from one in Australia has found evidence that an unfolded-protein-response can both activate and degrade the death receptor 5 protein ...
For the first time, researchers have observed at the molecular level how a protein associated with numerous health problems works.
Cell & Microbiology
Oct 3, 2019
0
213
(PhysOrg.com) -- University of Arkansas researchers have characterized a membrane receptor protein and its binding mechanism from chloroplasts in plants and determined that it shares a commonly shaped binding site and mechanism ...
Biochemistry
Jun 2, 2009
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4
Opioid drugs like morphine and fentanyl are a mainstay of modern pain medicine. But they also cause constipation, are highly addictive, and can lead to fatal respiratory failure if taken at too high a dose. Scientists have ...
Biochemistry
Jun 22, 2018
0
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