Cellular functions rely on several communications networks that allow cells to respond to signals affecting the organism. A new study published in Molecular Cell has revealed a mechanism that shuts down a major cell-to-cell ...
Cell & Microbiology
Jul 10, 2018
0
33
Opioid drugs like morphine and fentanyl are a mainstay of modern pain medicine. But they also cause constipation, are highly addictive, and can lead to fatal respiratory failure if taken at too high a dose. Scientists have ...
Biochemistry
Jun 22, 2018
0
74
One of the challenges of modern pharmacology is specificity. Despite therapeutic effects, drugs can often have side effects. The biological basis for this has to do with the proteins and receptors that the drug targets and ...
Biochemistry
Jun 18, 2018
0
84
For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects ...
Biochemistry
Jun 13, 2018
0
24
From burgers to steaks, beef has a long history of being a delicious part of dinner. But what if that pleasant experience of eating beef could extend beyond the dinner plate? Now, one group reports in ACS' Journal of Agricultural ...
Biochemistry
May 16, 2018
0
5
Using an informatics tool that identifies "hotspots" of post-translational modification (PTM) activity on proteins, researchers have found a previously-unknown mechanism that puts the brakes on an important cell signaling ...
Cell & Microbiology
May 7, 2018
0
74
T cells protect the body from foreign substances (known as antigens) and are an essential component of the body's immune system. New immunotherapies that use a patient's own T cells to treat disease have already proven strikingly ...
Bio & Medicine
Apr 30, 2018
0
34
A multi-institutional project to understand one of the major targets of human drug design has produced new insights into how structural communication works in a cell component called a G protein-coupled receptor (GPCRs), ...
Biochemistry
Apr 12, 2018
0
9
Researchers from MIPT and several U.S. and Chinese universities have solved the structure of one of the most important nervous system proteins in complex with a number of drug molecules. The discovery opens up opportunities ...
Biochemistry
Apr 2, 2018
0
29
A team of plant geneticists at Cold Spring Harbor Laboratory (CSHL) has identified a protein receptor on stem cells involved in plant development that can issue different instructions about how to grow depending on what peptide ...
Biotechnology
Mar 22, 2018
0
128
