A recent UCLA study demonstrates a new process for screening T cells, part of the body's natural defenses, for characteristics vital to the success of cell-based treatments. The method filters T cells based on the receptor ...
Bio & Medicine
Apr 15, 2024
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46
A team of bioengineers at Instituto Gulbenkian de Ciência, in Portugal, has found that inactivating the Tgfbr1 gene in mouse embryos results in altered development in the trunk to tail region.
Researchers at Karolinska Institutet in Sweden have used DNA origami, the art of folding DNA into desired structures, to show how an important cell receptor can be activated in a previously unknown way. The result opens new ...
Cell & Microbiology
Jan 18, 2024
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83
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable ...
Biochemistry
Dec 8, 2023
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8
Methamphetamine (meth) abuse is a major health concern. Understanding how meth interacts with its target proteins is crucial for the development of novel medications to address drug addiction. Previous research into the mechanism ...
Biochemistry
Nov 24, 2023
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53
Depression, obesity or chronic pain—all of these disorders can be triggered or promoted by stress. In two publications, researchers at TU Darmstadt show new ways of treating stress-related diseases.
Biochemistry
Nov 10, 2023
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53
Japanese scientist Kikunae Ikeda first proposed umami as a basic taste—in addition to sweet, sour, salty and bitter—in the early 1900s. About eight decades later, the scientific community officially agreed with him.
Cell & Microbiology
Oct 5, 2023
1
393
Signal transduction and perception regulates biological activities to adapt to changing environments. The Pert-Arnt-Sim domains are commonly available sensors found across diverse receptors in bacteria, eukaryotes, and archaea. ...
Wnt signaling is a well-known mode of cell-to-cell communication in multicellular biological organisms. It involves the secretion of small Wnt glycoproteins, by signaling cells, that bind to receptor proteins in the membrane ...
Molecular & Computational biology
Aug 3, 2023
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66
In a compost heap, the nematode Caenorhabditis elegans finds a richly laid table: at a length of just one millimeter, the worm feeds on bacteria that decompose organic material. It is essential that the animal avoids sunlight—and ...
Biotechnology
Aug 2, 2023
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4
