New research brings order to disordered proteins

Protein molecules lie at the heart of biology. Our typical understanding of proteins states that each type of protein has a specific three-dimensional shape that enables it to perform its function. This dogma is challenged ...

Scientists make COVID receptor protein in mouse cells

A team of scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Columbia University has demonstrated a way to produce large quantities of the receptor that SARS-CoV-2, the virus that causes ...

Shape-shifting protein study could advance new drug development

Proteins do the heavy lifting of performing biochemical functions in our bodies by binding to metabolites or other proteins to complete tasks. To do this successfully, protein molecules often shape-shift to allow specific ...

How cells accurately assemble complex machinery

Proteins are the workhorses of the cell, carrying out functions to keep everything running smoothly. Some proteins work on their own, but in other cases many proteins assemble together to create a complex machine. These proteins ...

New mapping method illuminates druggable sites on proteins

Identifying new ways to target proteins involved in human diseases is a priority for many researchers around the world. However, discovering how to alter the function of these proteins can be difficult, especially in live ...

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