Creating self-constructed folded macrocycles with low symmetry

The synthesis and self-organization of biological macromolecules is essential for life on earth. Ludwig Maximilian University of Munich chemists now report the spontaneous emergence of complex ring-shaped macromolecules with ...

Imaging method reveals a 'symphony of cellular activities'

Within a single cell, thousands of molecules, such as proteins, ions, and other signaling molecules, work together to perform all kinds of functions—absorbing nutrients, storing memories, and differentiating into specific ...

Sugar-coated viral proteins hijack and hitch a ride out of cells

Researchers from the Universities of Melbourne, York, Warwick and Oxford have shed light on how encapsulated viruses like hepatitis B, dengue and SARS-CoV-2 hijack the protein manufacturing and distribution pathways in the ...

Ice-binding molecules stop ice growth, act as natural antifreeze

Certain molecules bind tightly to the surface of ice, creating a curved interface that can halt further ice growth. Some insects, plants, and sea-dwelling creatures contain protein molecules of this type that act as natural ...

Transcription factors may inadvertently lock in DNA mistakes

Transcription factor proteins are the light switches of the human genome. By binding to DNA, they help turn genes 'on' or 'off' and start the important process of copying DNA into an RNA template that acts as a blueprint ...

Pediatric cancers share stalled gene-managing enzyme

A wildly out-of-place protein leads to haywire cells in a particularly troublesome type of rare early childhood cancer, according to University of Wisconsin–Madison researchers.

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