Related topics: protein

How do cellular machines unfold misfolded proteins?

Protein chains typically fold to function. Folding is a complex process and if done correctly leads to a unique functional fold topology for a given protein chain. Other topologies are also possible but are often non-functional ...

Remote control of transport through nanopores

In our bodies, the transfer of genetic information, viral infections and protein trafficking, as well as the synthesis and the degradation of biomolecules, are all phenomena that require the transport of molecules through ...

Chaperones just prepare proteins for folding on their own

Cellular proteins are produced as long chains of amino acids that must fold precisely into their final shape. The key players in this folding process are the so-called molecular chaperones, protein helpers that make sure ...

Shaping proteins to understand chaperone-related diseases

Chaperones are a set of proteins that are specialised to assist proteins in the human body. They help proteins to fold to the right shape and protect them from adapting wrong shapes. The research group of Alireza Mashaghi, ...

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