(PhysOrg.com) -- To study the behavior of large protein complexes and long DNA chains in solution, researchers use so-called molecular traps. However, earlier traps have proven ineffective when working with small molecules ...
A significant step forward in protein design from Generate Biomedicines, Massachusetts, has developed an AI that can generate feasible protein structures and predict the potential functionality of the proteins generated.
Plastic waste management is a pressing ecological, social, and economic challenge that has looked to diverse chemical-biology strategies to facilitate biodegradation. In a new report now on Science Advances, Mercedes Spinola-Amilibia ...
A protein complex prevents the repair of genome damage in human cells, in mice and in the nematode Caenorhabditis elegans, a team of researchers at the University of Cologne has discovered. They also successfully inhibited ...
Cell & Microbiology
Mar 23, 2023
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Whatever you are doing, whether it is driving a car, going for a jog, or even at your laziest, eating chips and watching TV on the couch, there is an entire suite of molecular machinery inside each of your cells hard at work. ...
Biochemistry
Jun 10, 2022
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593
The entire genomic material of a cell must be packed into a tiny cell nucleus in such a way, that on the one hand, it can be stored in an organized manner and, on the other hand, it can be transcribed, duplicated or repaired ...
Molecular & Computational biology
May 20, 2022
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In human chromosomes, DNA is coated by proteins to form an exceedingly long beaded string. This "string" is folded into numerous loops, which are believed to help cells control gene expression and facilitate DNA repair, among ...
Cell & Microbiology
Apr 14, 2022
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275
Humans need oxygen molecules for a process called cellular respiration, which takes place in our cells' mitochondria. Through a series of reactions called the electron transport chain, electrons are passed along in a sort ...
Cell & Microbiology
Dec 3, 2021
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Determining the 3-D shapes of biological molecules is one of the hardest problems in modern biology and medical discovery. Companies and research institutions often spend millions of dollars to determine a molecular structure—and ...
Molecular & Computational biology
Aug 26, 2021
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662
Alpha-actinin can cross-link actin filaments and anchor them to the Z-disk in sarcomeres. Sarcomeres are a structural unit of myofibril in striated muscle. The FATZ (filamin, α-actinin- and telethonin-binding protein of ...
