Related topics: cells · protein

How a large protein complex assembles in a cell

A team of ETH researchers led by Karsten Weis has developed a method that allows them to study the assembly process for large protein complexes in detail for the first time. As their case study, the biologists chose one of ...

Frozen: Cutting-edge technology reveals structures within cells

Temperatures of -196 degrees Celsius enable high-resolution imaging of the cell's interior. Researchers at the Institute of Science and Technology (IST) Austria are thus able to show for the first time how the active form ...

New 3-D structure of RNA polymerase III could lead to new treatments

Scientists have created a three-dimensional map of a complex of molecules that plays a fundamental role in life—and which when it goes wrong is linked to increased sensitivity to viral infections and neurodegenerative diseases.

Giving cells an appetite for viruses

A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in Nature, could lead to ways to manipulate this process to improve ...

A genetic shortcut to help visualize proteins at work

One of biologists' most vexing tasks is figuring out how proteins, the molecules that carry the brunt of a cell's work, do their job. Each protein has a variety of knobs, folds, and clefts on its surface that dictate what ...

Researchers peer inside deadly pathogen's burglary kit

The bacterium that causes the tick-borne disease tularemia is a lean, mean infecting machine. It carries a relatively small genome, and a unique set of infectious tools, including a collection of chromosomal genes called ...

Chromatin regulation enables generation of diverse antibodies

We need a variety of antibody types to help fight off invading foreign pathogens and our genome is exquisitely tuned to produce them to meet emerging needs. A new study finds that not just our DNA, but its configuration and ...

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