Growing HCA crystals

Zoë Fisher and Katarina Koruza from the ESS Deuteration and Macromolecular Crystallization (DEMAX) Support lab and Lund University have been using vapor diffusion methods to grow large protein crystals for neutron techniques ...

A 'biomultimeter' to measure RNA and protein production in real-time

Builders of genetic circuits face the same quandary as builders of digital circuits: testing their designs. Yet unlike bioengineers, engineers have a simple and universal testing tool—the multimeter—that they can touch ...

Key acid-activated protein channel identified

Johns Hopkins researchers have discovered a long-sought protein, the proton-activated chloride channel (PAC), that is activated in acidic environments and could protect against the tissue-damaging effects of stroke, heart ...

Location is everything for plant cell differentiation

While the fate of most human cells is determined by their lineage—for example, renal stem cells go on to form the kidney while cardiac progenitor cells form the heart—plant cells are a little more flexible. Research shows ...

Scientists discover common blueprint for protein antibiotics

A discovery by researchers at the Los Angeles Biomedical Research Institute (LA BioMed) has uncovered a common blueprint for proteins that have antimicrobial properties. This finding opens the door to design and development ...

A new approach to drugging a difficult cancer target

One of the most common cancer-promoting genes, known as Myc, is also one of the most difficult to target with drugs. Scientists have long tried to develop drugs that block the Myc protein, but so far their efforts have not ...

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