Researchers discover SARS-CoV-2 inhibitors

A research team of pharmacists at the University of Bonn has discovered two families of active substances that can block the replication of the SARS-CoV-2 coronavirus. The drug candidates are able to switch off the the key ...

Two-lock box delivers cancer therapy

Rice University scientists have designed a tunable virus that works like a safe deposit box. It takes two keys to open it and release its therapeutic cargo.

A 'biomultimeter' to measure RNA and protein production in real-time

Builders of genetic circuits face the same quandary as builders of digital circuits: testing their designs. Yet unlike bioengineers, engineers have a simple and universal testing tool—the multimeter—that they can touch ...

Transforming ARV treatment

Professor Yasien Sayed, research leader of the HIV Proteins Research Thrust, Protein Structure-Function Research Unit in the School of Molecular and Cell Biology, has led his group to international acclaim by solving the ...

An evolutionary method for reprogramming proteases

A team of researchers affiliated with multiple institutions in the U.S. has developed an evolutionary method for reprogramming proteases. In their paper published in the journal Science, the group describes how their technique ...

Two new weapons in the battle against bacteria

Proteases are vital proteins that serve for order within cells. They break apart other proteins, ensuring that these are properly synthesized and decomposed. Proteases are also responsible for the pathogenic effects of many ...

Essential process for SARS-CoV-2 viral replication visualized

During the replication of the SARS-CoV-2 virus, a long string of connected proteins is cleaved apart into individual proteins. This process is interrupted by an FDA-approved drug to treat COVID-19; however, the mechanistic ...

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