Experimental treatment regimen effective against HIV

Protease inhibitors are a class of antiviral drugs that are commonly used to treat HIV, the virus that causes AIDS. Scientists at the University of Nebraska Medical Center designed a new delivery system for these drugs that, ...

Progress toward the perfect pea

A group at the John Innes Centre has developed peas that will help animals absorb more protein from their diet. The study is published in PLOS ONE today.

Unpacking the mysteries of bacterial cell cycle regulation

As part of their long-term investigation of regulatory factors in the bacterial cell cycle, molecular biologists at the University of Massachusetts Amherst now report finding a surprising new role for one factor, CpdR, an ...

Researchers successfully target 'Achilles' heel' of MERS virus

A Purdue University-led team of researchers studying the Middle East Respiratory Syndrome, or MERS, have found molecules that shut down the activity of an essential enzyme in the virus and could lead the way to better treatments ...

Bacterial enzyme controls the degradation of defective proteins

A study by RIKEN researchers has revealed an important coping mechanism employed by enteric bacteria that allows them to thrive in environments with and without oxygen. The findings could help develop ways to control both ...

Some anti-inflammatory drugs affect more than their targets

Researchers have discovered that three commonly used nonsteroidal anti-inflammatory drugs, or NSAIDs, alter the activity of enzymes within cell membranes. Their finding suggests that, if taken at higher-than-approved doses ...

The difficult question of Clostridium difficile

The bacterium Clostridium difficile causes antibiotic-related diarrhoea and is a growing problem in the hospital environment and elsewhere in the community. Understanding how the microbe colonises the human gut when other ...

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