Must mRNA be cloaked in a lipid coat to serve as a vaccine?

The Uchida Laboratory of Innovation Center of NanoMedicine has demonstrated that intradermal administration of mRNA alone (naked mRNA) without protection by nanoparticles induced robust vaccination against SARS CoV-2, a virus ...

Rational design of mRNA nanovaccine for cancer immunotherapy

Messenger RNA (mRNA) vaccines are revolutionizing the therapy of cancer. They can be flexibly developed in a short period of time, allowing transient expression of multiple antigens for safe and efficient immunization. A ...

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