The clouds of spaghetti that keep DNA data safe

Cells can avoid "data breaches" when letting signaling proteins into their nuclei thanks to a quirky biophysical mechanism involving a blur of spaghetti-like proteins, researchers from the Rockefeller University and the Albert ...

Scientists map the portal to the cell's nucleus

Like an island nation, the nucleus of a cell has a transportation problem. Evolution has enclosed it with a double membrane, the nuclear envelope, which protects DNA but also cuts it off from the rest of the cell. Nature's ...

How shuttling proteins operate nuclear pores

Nuclear pore complexes are tiny channels where the exchange of substances between the cell nucleus and the cytoplasm takes place. Scientists at the University of Basel report on startling new research that might overturn ...

Colon cancer nuclear pore dynamics are captured by HS-AFM

One of the key reasons for cancer mortality is the highly invasive behaviour of cancer cells, which is often due to aggressive metastasis. Metastasis is facilitated by various growth factors and cytokines secreted from cells ...

Scientists reveal structure of nuclear pore's inner ring

It was a 3D puzzle with over 1000 pieces, with only a rather fuzzy outline as a guide. But scientists at EMBL have now put enough pieces in place to see the big picture. In a study published today in Science, they present ...

Nuclear pore complex successfully mapped and diagramed

(Phys.org)—Two teams of researchers taking different approaches have successfully mapped and diagramed the nuclear pore complex (NPC)—protein complexes that make up the pores in the nuclear envelope that allow or prevent ...

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