DNA base editing induces substantial off-target RNA mutations

In a study published in Nature on June 10, researchers from Dr. Yang Hui's Lab at the Institute of Neuroscience of the Chinese Academy of Sciences (CAS), and collaborators from the CAS-MPG Partner Institute for Computational ...

Minor genetic change creates unattractive female moths

Sex pheromones are chemical compounds released by an organism to attract potential mates. For moths in particular these sex pheromones are very important for mate recognition, as they rely completely on scent signal rather ...

Bioinformaticians examine new genes the moment they are born

Accumulating evidence suggests that new genes can arise spontaneously from previously non-coding DNA instead of through the gradual mutation of established genes. Bioinformaticians at the University of Münster (Germany) ...

More complex biological systems evolve more freely

Our genes (aka. the genotype) determine our characteristics (aka. the phenotype). Evolution acts on changes in the phenotype, which occur when mutations change the underlying genotype. But what changes to the phenotype can ...

Researchers clarify bacterial resistance

Just like plants and animals, bacteria have a range of defence mechanisms against viruses and other threats. Dutch researchers at the Wageningen Laboratory for Microbiology and their American and Russian colleagues have largely ...

Non-independent mutations present new path to evolutionary success

Mutations of DNA that lead to one base being replaced by another don't have to happen as single, independent events in humans and other eukaryotes, a group of Indiana University Bloomington biologists has learned after surveying ...

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