The start of a new era in stem cell therapy

A recent study published in the April 8 issue of Nature Chemical Biology improves on the "Cellular Reprogramming" method developed by Nobel Laureate in Medicine and Physiology Prof. Shinya Yamanaka, making it possible to ...

Spatial DNA organization forms first, then the rest

The fundamental organization of the DNA in active and inactive compartments arises immediately after fertilization of the oocyte, even before genes are activated. This was discovered by researchers from the Hubrecht Institute ...

Not all stem cells are created equal, study reveals

Researchers from the University of Toronto's Institute for Biomaterials and Biomedical Engineering (IBBME) and the Donnelly Centre have discovered a population of cells – dubbed to be "elite" – that play a key role in ...

Chimpanzee 'mini-brains' hint at secrets of human evolution

At some point during human evolution, a handful of genetic changes triggered a dramatic threefold expansion of the brain's neocortex, the wrinkly outermost layer of brain tissue responsible for everything from language to ...

3-D culturing hepatocytes on a liver-on-a-chip device

Liver-on-a-chip cell culture devices are attractive biomimetic models in drug discovery, toxicology and tissue engineering research. To maintain specific liver cell functions on a chip in the lab, adequate cell types and ...

The source of stem cells points to two proteins

Mammalian embryos are unlike those of any other organism as they must grow within the mother's body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such ...

Scientists mimic the earliest stages of human development

Human embryos start as a tiny mass of cells that are all the same. The first step in growing from a homogenous ball of cells into a complex individual with distinct organs and tissues is for the cells to divide into distinct ...

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